|Eddie Guerrero||July 27, 2003||Denver, CO||-a-|
|The Big Show||October 19, 2003||Baltimore, MD|
|John Cena||March, 14, 2004||New York, NY||-b-|
|Booker T.||July 27, 2004||Cincinnati, OH||-c-|
|John Cena ||October 3, 2004||East Rutherford, NJ||-d-|
|Carlito||October 5, 2004||Boston, MA|
|John Cena ||November 16, 2004||Dayton, OH|
|Orlando Jordan||March 1, 2005||Albany, NY|
|Chris Benoit||August 21, 2005||Washington DC|
|Booker T. ||October 18, 2005||Reno, NV||-e-|
|Booker T. ||January 10, 2006||Philadelphia, PA||-f-|
|Chris Benoit ||February 19, 2006||Balitimore, MD|
|John Bradshaw Layfield||April 2, 2006||Chicago, IL|
|Bobby Lashley||May 26, 2006||Bakersfield, CA|
|Finlay||July 11, 2006||Minneapolis, MN|
|Mr. Kennedy||August 29, 2006||Reading, PA||-g-|
|Chris Benoit ||October 10, 2006||Jacksonville, FL|
|Montel Vontavious Porter||May 19, 2007||St. Louis, MO|
|Matt Hardy||April 27, 2008||Baltimore, MD||-h-|
|Shelton Benjamin||July 20, 2008||Uniondale, NY||-i-|
|Montel Vontavious Porter ||March 17, 2009||Corpus Christi, TX||-j-|
-a- Defeats Chris Benoit in the finals of a tournament for the reinstated U.S. title. The belts lineage is traced back to the NWA United States Championship and the WCW United Staets Championship.
-b- Stripped and title declared vacant on July 6, 2004 in Winnipeg, MB after Cena attacks Smackdown General Manager Kurt Angle.
-c- Defeats Rob Van Dam in an eight-man elimination match to win the vacant title.
-d- Wins a best-of-five series.
-e- Title is held up after a match against Chris Benoit on November 21, 2005 in Sheffield, England ended in a draw, as both men's shoulders were down as two referees counted down both men.
-f- Defeats Chris Benoit in a best-of-seven series in which Randy Orton stood in for Booker T., gaining the fourth and decisive win.
-g- Defeats Finlay and Bobby Lashley in a triple threat match.
-h- Title becomes Raw exclusive after Hardy is drafted to Raw.
-i- Title returns to a Smackdown exclusive, as Benjamin is on Smackdown's roster.
-j- Title becomes a Raw exclusive again when MVP is drafted to Raw.